Ran two games of Blades at Total Confusion (Totalcon in Marlborough MA). Second time running it at a large con. I’d say it was very successful. Started things in media res with some premades and I definitely trimmed the downtime rules. With identical starting scenarios I ended up with wildly different (but positive) results and body counts. One person bought the PDF of the rules while we were playing, another went to the vendor booths while we took a short break to pick up the rules and I know at least one other person asked if they had the book at the vendor booth.
I highly recommend a large printed map as just a visual grounding for all the players. I kept my prep pretty minimal, but I did have some themes and ideas I wanted to touch on, that I could weave in as the story veered left and right. Downtime I kept to a single indulgence of vices with no risk of overindulgence and let players assign one skill dot of their choice.